Publications

Novel imaging tools to study mitochondrial morphology in Caenorhabditis elegans

Silvia Romero Sanz
DOI: 10.26508/lsa.202402918

Synergistic impact of N-antigenemia profiled by a rapid antigen test and low anti-S1 antibodies on the risk of hospitalization in COVID-19

Amanda De la Fuente Vazquez
PUBLICACION COMO PRIMERA AUTORA

Synergistic impact of innate immunity hyper-activation and endothelial dysfunction on the magnitude of organ failure in the infection-sepsis continuum

Amanda De la Fuente Vazquez
PUBLICACION COMO PRIMERA AUTORA

Publicación de un artículo en la revista Frontiers in Immunology

Cristina Aparicio Fernández
Publicación de un artículo titulado "MRGPRX2 signaling involves the Lysyl-tRNA synthetase and MITF pathway" en la revista Frontiers in Immunology. (DOI: 10.3389/fimmu.2023.1154108) (https://www.frontiersin.org/articles/10.3389/fimmu.2023.1154108/full)

Publicación de un artículo en la revista International Journal of Molecular Sciences

Cristina Aparicio Fernández
Publicación de la revisión "MITF Downregulation Induces Death in Human Mast Cell Leukemia Cells and Impairs IgE-Dependent Degranulation" perteneciente al número especial Mast Cells: From Host Defense to Pathology 2.0 de la revista International Journal of Molecular Sciences. (DOI: 10.3390/ijms24043515) (https://www.mdpi.com/1422-0067/24/4/3515)

Using C. elegans as a model for neurodegenerative diseases: Methodology and evaluation

Elena Caldero Escudero
Using C. elegans as a model for neurodegenerative diseases: Methodology and evaluation https://doi.org/10.1016/bs.mcb.2024.03.004

SERCA inhibition improves lifespan and healthspan in a chemical model of Parkinson disease in Caenorhabditis elegans (PAPER)

Elena Caldero Escudero
DOI 10.3389/fphar.2023.1182428

Aging AdipoR2-deficient mice are hyperactive with enlarged brains excessively rich in saturated fatty acids

Jorge Mondejar Duran
Ruiz M, Devkota R, Bergh PO, et al. Aging AdipoR2-deficient mice are hyperactive with enlarged brains excessively rich in saturated fatty acids. FASEB J. 2024;38(14):e23815. doi:10.1096/fj.202400293RR

Development of a novel in vitro model to study the modulatory role of the respiratory complex I in macrophage effector functions.

Maria Jesus Esteban Amo
Serrano-Lorenzo, P., Gobelli, D., Garrido-Moraga, R., Esteban-Amo, M. J., López-López, J. R., Orduña, A., de la Fuente, M. A., Martín, M. A., & Simarro, M. Development of a novel in vitro model to study the modulatory role of the respiratory complex I in macrophage effector functions. En: PLOS ONE. 19/09/2023, 18(9), e0291442. https://doi.org/10.1371/journal.pone.0291442

The mitochondrial succinate dehydrogenase complex controls the STAT3-IL-10 pathway in inflammatory macrophages.

Maria Jesus Esteban Amo
Gobelli, D., Serrano-Lorenzo, P., Esteban-Amo, M. J., Serna, J., Pérez-García, M. T., Orduña, A., Jourdain, A. A., Martín-Casanueva, M., Á. de la Fuente, M., & Simarro, M. The mitochondrial succinate dehydrogenase complex controls the STAT3-IL-10 pathway in inflammatory macrophages. En: IScience. 18/08/2023, 26(8), 107473. https://doi.org/10.1016/J.ISCI.2023.107473

Artículo titulado "Profiling of the genetic features of patients with breast, ovarian, colorectal and extracolonic cancers: Association to CHEK2 and PALB2 germline mutations", publicado en la revista Clinica Chimica Acta.

Mónica Arranz Ledo
https://doi.org/10.1016/j.cca.2023.117695

A Missense Variant in TP53 Could Be a Genetic Biomarker Associated with Bone Tissue Alterations

Nadia Regina Galindo Cabello
Autores: Ricardo Usategui-Martín, Nadia Galindo-Cabello, Salvador Pastor-Idoate, José María Fernández-Gómez, Álvaro del Real, Diego Ferreño, Rebeca Lapresa, Francisco Martín-Rodriguez, José A. Riancho, Ángeles Almeida, and José Luis Pérez-Castrillón Revista: International Journal of Molecular Sciences

ABSTRACT: Frequent TERT gains in metastatic papillary thyroid carcinoma - Annals Of Oncology

Sara Gil Bernabé
Publicación del Abstract del Póster presentado al Congreso ESMO 2023. Frequent TERT gains in metastatic papillary thyroid carcinoma. Annals of Oncology (2023) 34 (suppl_2): S1145-S1151. 10.1016/annonc/annonc1309 IF(2022):50.5

Using C. elegans as a model for neurodegenerative diseases: Methodology and evaluation

Silvia Romero Sanz
https://doi.org/10.1016/bs.mcb.2024.03.004

Publicación de una revisión en la revista Experimental Hematology & Oncology

Cristina Aparicio Fernández
Publicación de la revisión "Current approaches to develop “off-the-shelf” chimeric antigen receptor (CAR)-T cells for cancer treatment: a systematic review" en la revista Experimental Hematology & Oncology (https://doi.org/10.1186/s40164-023-00435-w) (https://ehoonline.biomedcentral.com/articles/10.1186/s40164-023-00435-w).

SLC25A46 promotes mitochondrial fission and mediates resistance to lipotoxic stress in INS-1E insulin-secreting cells

Elena Caldero Escudero
SLC25A46 promotes mitochondrial fission and mediates resistance to lipotoxic stress in INS-1E insulin-secreting cells. DOI: 10.1242/jcs.260049

Effects of Gestational Intermittent Hypoxia on Placental Morphology and Fetal Development in a Murine Model of Sleep Apnea.

Esther Valverde Pérez
DOI : 10.1007/978-3-031-32371-3 (Estimated Print Publication Date:Jul-2023).

Intermittent Hypoxia and Diet-Induced Obesity on the Intestinal Wall Morphology in a Murine Model of Sleep Apnea

Esther Valverde Pérez
DOI : 10.1007/978-3-031-32371-3 (Estimated Print Publication Date:Jul-2023).

Dual role of Apolipoprotein D as long-term instructive factor and acute signal conditioning microglial secretory and phagocytic responses

Jorge Mondejar Duran
Dual role of Apolipoprotein D as long-term instructive factor and acute signal conditioning microglial secretory and phagocytic responses 10.3389/fncel.2023.1112930

Antioxidants IJMS

Laura Sanchez Sanchez
Protective Actions of α-Tocopherol on Cell Membrane Lipids of Paraquat-Stressed Human Astrocytes Using Microarray Technology, MALDI-MS and Lipidomic Analysis

Publicación IJMS - MDPI

Laura Sanchez Sanchez
Characterization of the Antitumor Potential of Extracts of Cannabis sativa Strains with High CBD Content in Human NeuroblastCharacterization of the Antitumor Potential of Extracts of Cannabis sativa Strains with High CBD Content in Human Neuroblastomaoma

A Large Case-Control Study Performed in Spanish Population Suggests That RECQL5 Is the Only RECQ Helicase Involved in Breast Cancer Susceptibility

Mónica Arranz Ledo
Participación en el trabajo, titulado "A Large Case-Control Study Performed in Spanish Population Suggests That RECQL5 Is the Only RECQ Helicase Involved in Breast Cancer Susceptibility", publicado en la revista Cancers el 28 de septiembre de 2022.

Increased Co-Occurrence of Pathogenic Variants in Hereditary Breast and Ovarian Cancer and Lynch Syndromes: A Consequence of Multigene Panel Genetic Testing?

Mónica Arranz Ledo
Participación en el trabajo, titulado "Increased Co-Occurrence of Pathogenic Variants in Hereditary Breast and Ovarian Cancer and Lynch Syndromes: A Consequence of Multigene Panel Genetic Testing?", que fue publicado en la revista International Journal of Molecular Sciences el 29 de septiembre de 2022.

PUBLICACIÓN CAPÍTULO DE LIBRO: Renin-Angiotensin-Aldosterone System in Neurodegenerative Retinal Disorders

Nadia Regina Galindo Cabello
Título de la publicación: Renin-Angiotensin-Aldosterone System in Neurodegenerative Retinal Disorders Autores: Nadia Galindo Cabello; Salvador Pastor Idoate; Ricardo Usategui Martin. Libro: Horizons in Neuroscience Research. 49 - 979-8-88697-676-2, Nova Science Publishers. ISSN 1552-5783

Publicación artículo: "Silk-Elastin-like Polymers for Acute Intraparenchymal Treatment of the Traumatically Injured Spinal Cord: A First Systematic Experimental Approach"

Sara Escalera Anzola
González, P.; González-Fernández, C.; Maqueda, A.; Pérez, V.; Escalera-Anzola, S.; Rodríguez de Lope, Á.; Arias, F.J.; Girotti, A.; Rodríguez, F.J. Silk-Elastin-like Polymers for Acute Intraparenchymal Treatment of the Traumatically Injured Spinal Cord: A First Systematic Experimental Approach. Pharmaceutics 2022, 14, 2713. https://doi.org/10.3390/pharmaceutics14122713

ABSTRACT: CREBBP/EP300 disruption promotes tumor progression and confers synthetic lethality in anaplastic thyroid cancers.

Sara Gil Bernabé
Publicación del Abstract presentado en el AACR Annual Meeting 2023 en la revista Cancer Research. DOI: https://doi.org/10.1158/1538-7445.AM2023-3068

SERCA inhibition improves lifespan and healthspan in a chemical model of Parkinson disease in Caenorhabditis elegans

Silvia Romero Sanz
Enlace a la dirección del repositorio: https://www.frontiersin.org/articles/10.3389/fphar.2023.1182428/full

SLC25A46 promotes mitochondrial fission and mediates resistance to lipotoxic stress in INS-1E insulin-secreting cells

Silvia Romero Sanz
Enlace a la dirección del repositorio: https://journals.biologists.com/jcs/article-abstract/136/8/jcs260049/307067/SLC25A46-promotes-mitochondrial-fission-and?redirectedFrom=fulltext

Transcriptional Basis of Ca2+ Remodeling Reversal Induced by Polyamine Synthesis Inhibition in Colorectal Cancer Cells

Verónica Feijóo Salgado
Publicación del artículo "Transcriptional Basis of Ca2+ Remodeling Reversal Induced by Polyamine Synthesis Inhibition in Colorectal Cancer Cells" en la revista Cancers. https://doi.org/10.3390/cancers15051600

Splicing predictions, minigene analyses and ACMG/AMP clinical classification of 42 germline PALB2 splice-site variants

ALBERTO VALENZUELA PALOMO
PUBLICACIÓN UTILIZADA COMO AVAL DE TESIS

Low anti-SARS-CoV-2 S antibody levels predict increased mortality and dissemination of viral components in the blood of critical COVID-19 patients

Amanda De la Fuente Vazquez
Publicación científica

N-antigenemia detection by a rapid lateral flow test predicts 90-day mortality in COVID-19: a prospective cohort study

Amanda De la Fuente Vazquez
Publicación científica en Clinical Microbiology and Infection.

Publicación de una revisión en la revista International Journal of Molecular Sciences

Cristina Aparicio Fernández
Publicación de la revisión "Cell Therapy for Colorectal Cancer: The Promise of Chimeric Antigen Receptor (CAR)-T Cells" perteneciente al número especial Colorectal Cancer: From Pathophysiology to Novel Therapeutic Approaches 2021 de la revista International Journal of Molecular Sciences (https://doi.org/10.3390/ijms222111781) (https://www.mdpi.com/1422-0067/22/21/11781).

Fungal Patterns Induce Cytokine Expression through Fluxes of Metabolic Intermediates That Support Glycolysis and Oxidative Phosphorylation

Cristina Mancebo Tejera
Publicación en revista: The journal of immunology https://www.jimmunol.org/content/early/2022/06/10/jimmunol.2100666

Insulin-degrading enzyme ablation in mouse pancreatic alpha cells triggers cell proliferation, hyperplasia and glucagon secretion dysregulation.

Elena Casanueva Álvarez
Diabetologia 2022.

A first update on mapping the human genetic architecture of COVID-19 genetic architecture of COVID-19

Elisa Arribas Rodríguez
Publicado en la revista Nature el 03 de agosto de 2022

PUBLICACIÓN: CRISPR/CasRx Proof-of-Concept for RNA Degradation: A Future Tool against RNA Viruses'

Julia Serna Perez
Pharmaceuticals 2022, 15(1), 32; https://doi.org/10.3390/ph15010032

Analysis of mitochondrial function in cell membranes as indicator of tissue vulnerability to drugs in humans

Laura Sanchez Sanchez
Publicación de artículo en la revista Biomedicines

PAPER REMODELING OF INTRACELLULAR Ca2+HOMEOSTASIS IN RAT HIPPOCAMPASL NEURONS AGED IN VITRO

María Elena Hernando Pérez
ARTICULO/REVIEW: REMODELING OF INTRACELLULAR Ca2+ HOMEOSTASIS IN RAT HIPPOCAMPAL NEURONS AGED IN VITRO INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.24 FEBRUARY 2020

PAPER REMODELING OF INTRACELLULAR Ca2+HOMEOSTASIS IN RAT HIPPOCAMPASL NEURONS AGED IN VITRO

María Elena Hernando Pérez
ARTICULO/REVIEW: REMODELING OF INTRACELLULAR Ca2+ HOMEOSTASIS IN RAT HIPPOCAMPAL NEURONS AGED IN VITRO INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.24 FEBRUARY 2020

PAPER REMODELING OF INTRACELLULAR Ca2+HOMEOSTASIS IN RAT HIPPOCAMPASL NEURONS AGED IN VITRO

María Elena Hernando Pérez
ARTICULO/REVIEW: REMODELING OF INTRACELLULAR Ca2+HOMEOSTASIS IN RAT HIPPOCAMPASL NEURONS AGED IN VITRO INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.24 FEBRUARY 2020

Programmed cell death and autophagy during retinal neurodegeneration

Nadia Regina Galindo Cabello
K.Puertas Neyra; N. Galindo Cabello; L. Hernández Rodríguez; F. González Pérez; J.C. Rodriguez Cabello; R. González Sarmiento; J.C. Pastor; R. Usategui Martin; I. Fernandez Bueno.Programmed cell death and autophagy during retinal neurodegeneration.2022,v16.,pp1-14.10.3389/fnana.2022.812487

Retinal Neuroprotective Effect of Mesenchymal Stem Cells Secretome Through Modulation of Oxidative Stress, Autophagy, and Programmed Cell Death

Nadia Regina Galindo Cabello
R. Usategui Martin; K. Puertas Neyra; N. Galindo Cabello; L. Hernández Rodríguez; F. González Pérez; J.C. Rodriguez Cabello; R. González Sarmiento; J.C. Pastor; I. Fernandez Bueno. Retinal Neuroprotective Effect of Mesenchymal Stem Cells Secretome Through Modulation of Oxidative Stress, Autophagy, and Programmed Cell Death.2022,v.63,n°4,pp27. https://doi.org/10.1167/iovs.63.4.27

Publicación Capítulo de libro "Designing Elastin-Like Recombinamers for Therapeutic and Regenerative Purposes"

Sara Escalera Anzola
Rodríguez-Cabello, J.C., Escalera ☆ , S., Juanes-Gusano ☆ , D., Santos, M. and Girotti, A. (2022). Designing Elastin-Like Recombinamers for Therapeutic and Regenerative Purposes. In Multifunctional Hydrogels for Biomedical Applications (eds R.A. Pires, I. Pashkuleva and R.L. Reis). https://doi.org/10.1002/9783527825820.ch3

Publicación capítulo de libro "Elastin-like Polymers as Nanovaccines: Protein Engineering of Self-Assembled, Epitope-Exposing Nanoparticles"

Sara Escalera Anzola
Girotti, A., González-Valdivieso, J., Alonso-Sampedro, I., Escalera-Anzola, S., Ramos-Díez, S., Arias, F.J. (2022). Elastin-like Polymers as Nanovaccines: Protein Engineering of Self-Assembled, Epitope-Exposing Nanoparticles. In: Brun, A. (eds) Vaccine Technologies for Veterinary Viral Diseases. Methods in Molecular Biology, vol 2465. Humana, New York, NY.

Remodeling of Intracellular Ca2+ Homeostasis in Rat Hippocampal Neurons Aged In Vitro

Sara López Vázquez
Calvo-Rodríguez M, Hernando-Pérez E, López-Vázquez S, Núñez L, Villalobos C, Intracellular calcium remodeling in rat hippocampal neurons aged in vitro, International Journal of Molecular Sciences, 2020, doi: 10.3390/ijms21041549, Q1 IF: 4,3.

Publicación Revisión "Aptamer-Functionalized Natural Protein-Based Polymers as Innovative Biomaterials"

Sara Escalera Anzola
Girotti, A.; Escalera-Anzola, S.; Alonso-Sampedro, I.; González-Valdivieso, J.; Arias, F.J. Aptamer-Functionalized Natural Protein-Based Polymers as Innovative Biomaterials. Pharmaceutics 2020, 12, 1115. https://doi.org/10.3390/pharmaceutics12111115

ABSTRACT: A comprehensive study of the role of EIF1AX mutations in anaplastic thyroid carcinomas. Relationship with established mutational events, tumor progression and dedifferentiation

Sara Gil Bernabé
Publicación del Abstract del Congreso ESMO 2021 en Annals of Oncology IF: 32.976 (2020).

Publicacion en The FEBS Journal: "Clinically used JAK inhibitor blunts dsRNA-induced inflammation and calcification in aortic valve interstitial cells" en el cual soy primera autora junto con Iván Parra-izquierdo (*=coautoría)

Tania Sánchez-Bayuela Recio
Publicacion en The FEBS Journal: "Clinically used JAK inhibitor blunts dsRNA-induced inflammation and calcification in aortic valve interstitial cells" en el cual soy primera autora junto con Iván Parra-izquierdo (*=coautoría) https://pubmed.ncbi.nlm.nih.gov/34009721/

Publicación en International Journal of Molecular Sciences. "Interferons Are Pro-Inflammatory Cytokines in Sheared-Stressed Human Aortic Valve Endothelial Cells"

Tania Sánchez-Bayuela Recio
Publicación en International Journal of Molecular Sciences. "Interferons Are Pro-Inflammatory Cytokines in Sheared-Stressed Human Aortic Valve Endothelial Cells" https://pubmed.ncbi.nlm.nih.gov/34638942/

Colaboración en la publicación de un artículo científico

Aida Fiz López
Morales, A. et al. Growth arrest-specific factor 6 (Gas6) is increased in covid-19 patients and predicts clinical outcome. Biomedicines 9, 1–11 (2021).

Publicación: Novel fluorescent-based reporter cell line engineered for monitoring homologous recombination events

Julia Serna Perez
Bernardi A, Gobelli D, Serna J, Nawrocka P, March-Rosselló G, Orduña A, Kozlowski P, Simarro M, de la Fuente MA. Novel fluorescent-based reporter cell line engineered for monitoring homologous recombination events. PLoS One. 2021 Apr 30;16(4):e0237413. doi: 10.1371/journal.pone.0237413. PMID: 33930025; PMCID: PMC8087102.

Publicación científica

MIGUEL ANGEL BERMUDEZ ARIAS
Publicación científica como coautor del artículo: Astudillo, A.M., Meana, C., Bermúdez, M.A., Pérez-Encabo, A., Balboa, M.A. & Balsinde, J. (2020) Release of anti-inflammatory palmitoleic acid and its positional isomers by mouse peritoneal macrophages. Biomedicines 8: 480.

Abstract PO-005: Spatio-temporal geographical molecular mapping of primary papillary thyroid carcinomas and paired distant metastases: Clinical relevance for monitoring and targeting tumor heterogeneity

Sara Gil Bernabé
Tipo de comunicación: Virtual Poster Congreso: Virtual Special Conference: Tumor Heterogeneity: From Single Cells to Clinical Impact Entidad organizadora: AACR (American Association for Cancer Research) DOI: 10.1158/1538-7445.TUMHET2020-PO-005 Fecha de publicación: Noviembre 2020 Revista: Cancer Research Factor de Impacto: 12.701 (2020)

Publicación en FEBS. "Clinically used JAK inhibitor blunts dsRNA-induced inflammation and calcification in aortic valve interstitial cells"

Tania Sánchez-Bayuela Recio
Publicación en FEBS: "Clinically used JAK inhibitor blunts dsRNA-induced inflammation and calcification in aortic valve interstitial cells" Ivan Parra-Izquierdo* , Tania Sanchez-Bayuela*, Irene Casta~nos-Mollor, Javier Lopez, Cristina Gomez1, J. Alberto San Roman, Mariano Sanchez Crespo and Carmen Garcıa-Rodrıguez. *coautores

MR- proADM to detect specific types of organ failure in infection.

CRISTINA ANDRES LEDESMA
Publicación en la revista European Journal of Clinical Investigation

Publicación: Myocardin-Dependent Kv1.5 Channel Expression Prevents Phenotypic Modulation of Human Vessels in Organ Culture

Julia Serna Perez
Publicación: Myocardin-Dependent Kv1.5 Channel Expression Prevents Phenotypic Modulation of Human Vessels in Organ Culture. ATVB. December 2019, Vol 39, Issue 12. https://doi.org/10.1161/ATVBAHA.119.313492

"UGT1A1 Variants c.864+5G>T and c.996+2_996+5del of a Crigler-Najjar Patient Induce Aberrant Splicing in Minigene Assays"

Lara Sanoguera Miralles
Tercera autora del artículo de título "UGT1A1 Variants c.864+5G>T and c.996+2_996+5del of a Crigler-Najjar Patient Induce Aberrant Splicing in Minigene Assays" publicado el 6 de marzo del año 2020 en la revista Frontiers in Genetics.

PAPER REMODELING OF INTRACELLULAR Ca2+HOMEOSTASIS IN RAT HIPPOCAMPASL NEURONS AGED IN VITRO

María Elena Hernando Pérez
ARTICULO/REVIEW: REMODELING OF INTRACELLULAR Ca2+HOMEOSTASIS IN RAT HIPPOCAMPASL NEURONS AGED IN VITRO INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.24 FEBRUARY 2020

Lymphocytopenia as a Predictor of Mortality in Patients with ICU-Acquired Pneumonia. J Clin Med.

MARTA MARTIN FERNÁNDEZ
doi: 10.3390/jcm8060843.

Endothelial Dysfunction Is an Early Indicator of Sepsis and Neutrophil Degranulation of Septic Shock in Surgical Patients. BJS Open

MARTA MARTIN FERNÁNDEZ
DOI: 10.1002/bjs5.50265

Current gaps in sepsis immunology: new opportunities for translational research. Lancet Infectious Diseases

MARTA MARTIN FERNÁNDEZ
doi: 10.1016/S1473-3099(19)30567-5

Composed endotypes to guide antibiotic discontinuation in sepsis. Crit. Care

MARTA MARTIN FERNÁNDEZ
doi: 10.1186/s13054-019-2439-0.

MR- proADM to detect specific types of organ failure in infection. Eur J Clin Invest.

MARTA MARTIN FERNÁNDEZ
doi: 10.1111/eci.13246.

Lipid-Binding Proteins in Brain Health and Disease

MIRIAM CORRALIZA GOMEZ
Publicación de la Revisión "Lipid-Binding Proteins in Brain Health and Disease" en la revista "Frontiers in Neurology" doi: 10.3389/fneur.2019.01152

The MTT-formazan assay: Complementary technical approaches and in vivo validation in Drosophila larvae

MIRIAM CORRALIZA GOMEZ
Este artículo fue publicado en enero de 2018, pero el curso pasado se me olvidó subirlo a mi Documento de Actividades. Lo incluyo ahora porque la convocatoria de becas de movilidad de la UVa de este año va a tener en cuenta como historial científico de los solicitantes su SIGMA-UVa. https://doi.org/10.1016/j.acthis.2018.01.006

Apolipoprotein D-mediated preservation of lysosomal function promotes cell survival and delays motor impairment in Niemann-Pick type A disease

MIRIAM CORRALIZA GOMEZ
Apolipoprotein D-mediated preservation of lysosomal function promotes cellsurvival and delays motor impairment in Niemann-Pick type A disease. Raquel Pascua-Maestro, Miriam Corraliza-Gomez, Cristian Fadrique-Rojo, Maria D. Ledesma,Edward H. Schuchman, Diego Sanchez, Maria D. Ganfornina Neurobiology of disease 144 (2020) https://doi.org/10.1016/j.nbd.2020.105046

Modulation of Glial Responses by Furanocembranolides: Leptolide Diminishes Microglial Inflammation in Vitro and Ameliorates Gliosis In Vivo in a Mouse Model of Obesity and Insulin Resistance

MIRIAM CORRALIZA GOMEZ
Modulation of Glial Responses by Furanocembranolides: Leptolide Diminishes Microglial Inflammation in Vitro and Ameliorates Gliosis In Vivo in a Mouse Model of Obesity and Insulin Resistance Marine Drugs, 22 July 2020 DOI: 10.3390/md18080378

PUBLICACIÓN REVIEW "The role of calcium signaling in Aging and Neurodegeneration: Insights fro Caenorhabditis elegant Models.

PALOMA GARCÍA CASAS
Alvarez J, Alvarez-Illera P, García-Casas P, Fonteriz RI, Montero M. The Role of Ca2+ Signaling in Aging and Neurodegeneration: Insights from Caenorhabditis elegans models. Cells, 2020. 9(1) pii E204.

ABSTRACT: SPATIOTEMPORAL INTRATUMOR GENETIC HETEROGENEITY AND CLONAL EVOLUTION IN PTCS AND PAIRED DM. ANNALS OF ONCOLOGY.

Sara Gil Bernabé
“Spatiotemporal intratumor genetic heterogeneity and clonal evolution in PTCs and paired DM” Tipo de comunicación: Poster Discussion Publicación en: ESMO 2019 Abstract Book, (Supplement) Revista: Annals of Oncology DOI: https://doi.org/10.1093/annonc/mdz267.002 https://academic.oup.com/annonc/article/30/Supplement_5/mdz267.0 02/5578209 IF- 2018- JCR: 14.196

Genetically engineered elastin-like recombinamers with sequence-based molecular stabilization as advanced bioinks for 3D bioprinting

SORAYA SALINAS FERNÁNDEZ
Acceso al artículo científico (open access): https://www.sciencedirect.com/science/article/pii/S2352940719306195

Mis-splicing in breast cancer: identification of pathogenic BRCA2 variants by systematic minigene assays.

ALBERTO VALENZUELA PALOMO
The Journal of Pathology

Alternative splicing and ACMG-AMP-2015-based classification of PALB2 genetic variants: an ENIGMA report.

ALBERTO VALENZUELA PALOMO
Journal of Medical Genetics

Tricarboxylic Acid Cycle Activity and Remodeling of Glycerophosphocholine Lipids Support Cytokine Induction in Response to Fungal Patterns.

Cristina Mancebo Tejera
Tricarboxylic Acid Cycle Activity and Remodeling of Glycerophosphocholine Lipids Support Cytokine Induction in Response to Fungal Patterns. Cell Reports

Publication in Biomedical Materials (IOP Science)

Filippo Cipriani
Bicyclic RGD peptides with high integrin αvβ3 and α5β1 affinity promote cell adhesion on elastin-like recombinamers https://iopscience.iop.org/article/10.1088/1748-605X/aafd83

Publicacion en Biomacromolecules (ACS Journal)

Filippo Cipriani
https://pubs.acs.org/doi/10.1021/acs.biomac.8b01211

Publication in Regenerative Biomaterials (Oxford Academic)

Filippo Cipriani
An elastin-like recombinamer-based bioactive hydrogel embedded with mesenchymal stromal cells as an injectable scaffold for osteochondral repair. https://academic.oup.com/rb/advance-article/doi/10.1093/rb/rbz023/5492343

Publicación de artículo: Lipopolysaccharide and interferon-γ team up to activate HIF-1 via STAT1 in normoxia and exhibit sex differences in human aortic valve interstitial cells.

IRENE CASTAÑOS-MOLLOR MORCILLO
Lipopolysaccharide and interferon-γ team up to activate HIF-1 via STAT1 in normoxia and exhibit sex differences in human aortic valve interstitial cells. Iván Parra-Izquierdo, Irene Castaños-Mollor, Javier López,Cristina Gómez, J Alberto San Román, Mariano Sánchez Crespo, Carmen García-Rodríguez DOI: 10.1016/j.bbadis.2019.04.014

Publicación de un artículo de Investigación

IVÁN PARRA IZQUIERDO
Artículo original de investigación: Lipopolysaccharide and interferon-γ team up to activate HIF-1; via STAT1 in normoxia and exhibit sex differences in human aortic valve interstitial cells. Parra-Izquierdo I, Castaños-Mollor I, López J, Gómez C, San Román JA, Sánchez Crespo M, García-Rodríguez C. Biochim Biophys Acta Mol Basis Dis. 2019 Apr 26.

cell reports

Jose Javier Fernandez Rodriguez
Tricarboxylic Acid Cycle Activity and Remodeling of Glycerophosphocholine Lipids Support Cytokine Induction in Response to Fungal Patterns

Vázquez, P., Hernández-Sánchez, C., Escalona-Garrido, C., Pereira, L., Contreras, C., López, M., Balsinde, J., de Pablo, F. & Valverde, Á.M. (2018) Increased FGF21 in brown adipose tissue of tyrosine hydroxylase heterozygous mice: implications for cold adaptation. J Lipid Res 59(12):2308-2320

LAURA PEREIRA DE BLAS
Vázquez, P., Hernández-Sánchez, C., Escalona-Garrido, C., Pereira, L., Contreras, C., López, M., Balsinde, J., de Pablo, F. & Valverde, Á.M. (2018) Increased FGF21 in brown adipose tissue of tyrosine hydroxylase heterozygous mice: implications for cold adaptation. J Lipid Res 59(12):2308-2320

Guijas, C., Bermúdez, M.A., Meana, C., Astudillo, A.M., Pereira, L., Fernández-Caballero, L., Balboa, M.A. & Balsinde J. (2019) Neutral lipids are not a source of arachidonic acid for lipid mediator signaling in human foamy monocytes. Cells 8: 941

LAURA PEREIRA DE BLAS
Guijas, C., Bermúdez, M.A., Meana, C., Astudillo, A.M., Pereira, L., Fernández-Caballero, L., Balboa, M.A. & Balsinde J. (2019) Neutral lipids are not a source of arachidonic acid for lipid mediator signaling in human foamy monocytes. Cells 8: 941.

"TRPC1 and Orai1 channels in colon cancer"

LUCÍA GONZÁLEZ GUTIÉRREZ
Artículo de Investigación: Villalobos C1, Hernández-Morales M2, Gutiérrez LG3, Núñez L3. TRPC1 and ORAI1 channels in colon cancer. Cell Calcium. 2019 Jul;81:59-66.

Inhibition of polyamine biosynthesis reverses Ca2+ channel remodeling in colon cancer cells

LUCÍA GONZÁLEZ GUTIÉRREZ
Publicación en Cancers Journal Q1; https://www.mdpi.com/2072-6694/11/1/83

"Mitochondrial control... in cancer: Pharmacological implications"

LUCÍA GONZÁLEZ GUTIÉRREZ
Artículo de investigación en la revista "Pharmacological Research" Villalobos C1, Gutiérrez LG2, Hernández-Morales M3, Del Bosque D2, Núñez L4.Mitochondrial control of store-operated Ca2+ channels in cancer: Pharmacological implications.Pharmacol Res. 2018 Sep;135:136-143

Cefalea: embarazo y lactancia. Recomendaciones del Grupo de Estudio de Cefaleas de la Sociedad Española de Neurología (GECSEN)

MARINA RUIZ PIÑERO
coautora

Congestión nasal como síntoma autonómico acompañante de crisis migrañosas

MARINA RUIZ PIÑERO
coautor

"Shared Features of Endothelial Dysfunction between Sepsis and Its Preceding Risk Factors (Aging and Chronic Disease)". Journal of Clinical Medicine

MARTA MARTIN FERNÁNDEZ
Artículo como co-primera autora en la revista Scientific Reports, de 1º decil

Guijas, C., Bermúdez, M.A., Meana, C., Astudillo, A.M., Pereira, L., Fernández-Caballero, L., Balboa, M.A. & Balsinde J. (2019) Neutral lipids are not a source of arachidonic acid for lipid mediator signaling in human foamy monocytes. Cells 8: 941

MIGUEL ANGEL BERMUDEZ ARIAS
Coautor del siguiente trabajo científico: Guijas, C., Bermúdez, M.A., Meana, C., Astudillo, A.M., Pereira, L., Fernández-Caballero, L., Balboa, M.A. & Balsinde J. (2019) Neutral lipids are not a source of arachidonic acid for lipid mediator signaling in human foamy monocytes. Cells 8: 941

PUBLICACIÓN EN FRONTIERS AGING NEUROSCIENCE

PALOMA GARCÍA CASAS
PUBLICACIÓN DEL SEGUNDO ARTÍCULO DERIVADO DE LOS RESULTADOS DE LA TESIS DOCTORAL.

ABSTRACT: “Spatio-temporal genetic heterogeneity and clonal evolution in advanced papillary thyroid carcinomas and matched distant metastases.” Revista: Cancer Research 2019; 79(13 Suppl).

Sara Gil Bernabé
Autores: Sara Gil-Bernabé, Noa Feas Rodríguez, Miriam Vega Herrero, Jose Javier Estébanez García, Ginesa M. Garcia-Rostan. Título: “Spatio-temporal genetic heterogeneity and cAbstract reference: 2770. Revista: Cancer Res 2019; 79(13 Suppl). DOI: 10.1158/1538-7445.SABCS18-2770 Fecha: Julio 2019 http://cancerres.aacrjournals.org/content/79/13_Supplement/2770 IF- 2018- JCR: 8.378

Publicacion en Revista cientifica. Elsevier. "Comparative analysis study of two assays for anti-DFS70 antibodies determination"

SOFIA AMELIA PEREZ ZARAGOZA
Publicacion en Revista cientifica. Elsevier. "Comparative analysis study of two assays for anti-DFS70 antibodies determination" Autores:A. Esteban, B. Aparicio, S. Lorenzo, S. Perez Zaragoza, P. Garcia Fernandez-Rufete, L. Llorca. doi:10.1016/j.cca.2019.03.198 Presentado en EuroMedLab 2019 como miembro de la Comisión de Bioquímica de Enfermedades Inmunológicas de la SEQC.

Papel de las formas inmaduras en Sepsis

CRISTINA ANDRES LEDESMA
Combined quantification of procalcitonin and HLA-DR improves sepsis detection in surgical patients

COMBINED QUANTIFICATION OF PROCALCITONIN AND HLA-DR IMPROVES SEPSIS DETECTION IN SURGICAL PATIENTS

CRISTINA ANDRES LEDESMA
COMBINED QUANTIFICATION OF PROCALCITONIN AND HLA-DR IMPROVES SEPSIS DETECTION IN SURGICAL PATIENTS

QUANTIFICATION OF IMMUNE DYSREGULATION BY NEXT-GENERATION POLYMERASE CHAIN REACTION TO IMPROVE SEPSIS DIAGNOSIS IN SURGICAL PATIENTS

CRISTINA ANDRES LEDESMA
QUANTIFICATION OF IMMUNE DYSREGULATION BY NEXT-GENERATION POLYMERASE CHAIN REACTION TO IMPROVE SEPSIS DIAGNOSIS IN SURGICAL PATIENTS. Ann Surg. 2017 Jul 7. Factor de impacto: 8,980.

EL PARADIGMA DE LA SEPSIS: EN BUSCA DEL BIOMARCADOR PERFECTO

CRISTINA ANDRES LEDESMA
Editorial en la Revista del Laboratorio Clínico

“Insulin degrading enzyme is up-regulated in pancreatic β cells by insulin treatment.” Revista: Histol. and Hispopathology Fecha: May 2018

Cristina María Fernández Díaz
https://www.ncbi.nlm.nih.gov/pubmed/29726577

"Protective effects of epoxypukalide on pancreatic beta‐cells and glucose metabolism in STZinduced diabetic mice" Revista: Islets. Fecha: Mar 2015

Cristina María Fernández Díaz
https://www.ncbi.nlm.nih.gov/pubmed/26406478

Artículo: "Calcification Induced by Type I Interferon in Human Aortic Valve Interstitial Cells Is Larger in Males and Blunted by a Janus Kinase Inhibitor"

IRENE CASTAÑOS-MOLLOR MORCILLO
"Calcification Induced by Type I Interferon in Human Aortic Valve Interstitial Cells Is Larger in Males and Blunted by a Janus Kinase Inhibitor" Iván Parra-Izquierdo , Irene Castaños-Mollor , Javier López , Cristina Gómez , J. Alberto San Román , Mariano Sánchez Crespo and Carmen García-Rodríguez 2018;0:ATVBAHA.118.311504

MINI REVIEW ARTICLE

IRENE CASTAÑOS-MOLLOR MORCILLO
MINI REVIEW ARTICLE Front. Physiol., 12 March 2018 | https://doi.org/10.3389/fphys.2018.00201 "Toll-Like Receptors, Inflammation, and Calcific Aortic Valve Disease" Carmen García-Rodríguez, Iván Parra-Izquierdo, Irene Castaños-Mollor, Javier López, J. Alberto San Román and Mariano Sánchez Crespo

Publicación de un articulo original de Investigación

IVÁN PARRA IZQUIERDO
https://www.ncbi.nlm.nih.gov/pubmed/30026273

Publicación de una mini-revisión en Frontiers in Physiology

IVÁN PARRA IZQUIERDO
Título: Toll-Like Receptors, Inflammation,and Calcific Aortic Valve Disease

Artículo de Investigación

JESICA ARIAS DEL VAL
Inhibition of Sarco-Endoplasmic Reticulum Ca2+ ATPase Extends the Lifespan in C. elegans Worms

Front Immunol. 2017 Jun 19;8:639. doi: 10.3389/fimmu.2017.00639. eCollection 2017.

Jose Javier Fernandez Rodriguez
Front Immunol. 2017 Jun 19;8:639. doi: 10.3389/fimmu.2017.00639. eCollection 2017. Endoplasmic Reticulum Stress Sensor IRE1α Enhances IL-23 Expression by Human Dendritic Cells. Márquez S1, Fernández JJ1, Terán-Cabanillas E2,3,4, Herrero C5, Alonso S5, Azogil A5, Montero O6, Iwawaki T7, Cubillos-Ruiz JR2,3, Fernández N1,5, Crespo MS5.

Coautor en Cápitulo: 4 Elastin-like proteins: Molecular design for self-assembling

MARCOS HERRERO GUTIERREZ
https://doi.org/10.1016/B978-0-08-102015-9.00004-6 Pages 49–78 Chapter: 4 Elastin-like proteins: Molecular design for self-assembling Book: Self-assembling Biomaterials Author: Jose C. Rodríguez-Cabello,Israel González de Torre,Sergio Acosta,Soraya Salinas,Marcos Herrero Publisher: Elsevier Date: 2018

Artículo "Tuning the Stiffness of Surfaces by Assembling Genetically Engineered Polypeptides with Tailored Amino Acid Sequence"

MARCOS HERRERO GUTIERREZ
Artículo publicado en la revista Biomacromolecules. DOI: 10.1021/acs.biomac.8b00723

Identification of Eight Spliceogenic Variants in BRCA2 Exon 16 by Minigenes Assays.

MARIA EUGENIA FRAILE BETHENCOURT
Fraile-Bethencourt E., Valenzuela-Palomo A., Díez-Gómez B., Acedo A. & Velasco EA. Frontiers in Genetics 2018. Identification of Eight Spliceogenic Variants in BRCA2 Exon 16 by Minigenes Assays. Doi: 10.3389/fgene.2018.00188

Characterization of spliceogenic variants located in regions linked to high levels of alternative splicing: BRCA2 c.7976+5G > T as a case study.

MARIA EUGENIA FRAILE BETHENCOURT
Montalban, G., Fraile-Bethencourt, E., López-Perolio, I., Pérez-Segura, P., Infante, M., Durán, M., et al. (2018). Characterization of spliceogenic variants located in regions linked to high levels of alternative splicing: BRCA2 c.7976+5G > T as a case study. Hum. Mutat., 1–6. doi:10.1002/humu.23583.

Genetic dissection of the BRCA2 promoter and transcriptional impact of DNA variants

MARIA EUGENIA FRAILE BETHENCOURT
Fraile-Bethencourt E, Valenzuela-Palomo A, Díez-Gómez B, Infante M, Durán M, Marcos G, Lastra E, Gómez-Barrero S & Velasco EA (2018) Genetic dissection of the BRCA2 promoter and transcriptional impact of DNA variants. Breast Cancer Research and Treatment. Available at: https://doi.org/10.1007/s10549-018-4826-7

Role of reactive oxygen species and sulfide-quinone oxoreductase in hydrogen sulfide-induced contraction of rat pulmonary arteries.

MARÍA INMACULADA DOCIO CUADRADO
Role of reactive oxygen species and sulfide-quinone oxoreductase in hydrogen sulfide-induced contraction of rat pulmonary arteries. Prieto-Lloret J, Snetkov VA, Shaifta Y, Docio I, Connolly MJ, MacKay CE, Knock GA, Ward JPT, Aaronson PI. Am J Physiol Lung Cell Mol Physiol. 2018 Apr 1;314(4):L670-L685. doi: 10.1152/ajplung.00283.2016. Epub 2017 Dec 28.

Guinea Pig as a model to study the carotid body mediated chronic intermittent hypoxia effects.

MARÍA INMACULADA DOCIO CUADRADO
Guinea Pig as a model to study the carotid body mediated chronic intermittent hypoxia effects. Inmaculada Docio, Elena Olea, Jesus Prieto-Lloret, Teresa Gallego, Ana Obeso, Angela Gomez-Niño, Asunción Rocher. Front. Physiol. 9:694. doi: 10.3389/fphys.2018.00694

Mitochondrial Complex I dysfunction and peripheral chemoreflex sensitivity in a FASTK-deficient mice model.

MARÍA INMACULADA DOCIO CUADRADO
Mitochondrial Complex I dysfunction and peripheral chemoreflex sensitivity in a FASTK-deficient mice model. Angela Gomez-Niño, Inmaculada Docio, Jesus Prieto-Lloret, Maria Simarro, Miguel A. de la Fuente, Asuncion Rocher. Adv Exp Med Biol (in press).

Effect of general anaesthesia on functional outcome in patients with anterior circulation ischaemic stroke having endovascular thrombectomy versus standard care: a meta-analysis of individual patient data.

MARINA RUIZ PIÑERO
Autor colaborador.

Pre-sepsis: A necessary concept to complete the SEPSIS-3 picture' Journal of Critical Care

MARTA MARTIN FERNÁNDEZ
Publicado en Journal of Critical Care

"Combined quantification of procalcitonin and HLA-DR improves sepsis detection in surgical patients". Scientific Reports

MARTA MARTIN FERNÁNDEZ
Artículo como co-primera autora en la revista Scientific Reports, de 1º cuartil.

Immunological profiling to assess disease severity and prognosis in community-acquired pneumonia. Lancet Respiratory Medicine

MARTA MARTIN FERNÁNDEZ
Publicado en Lancet Respiratory Medicine

Quantification of Immune Dysregulation by Next-generation Polymerase Chain Reaction to Improve Sepsis Diagnosis in Surgical Patients. Annals of Surgery.

MARTA MARTIN FERNÁNDEZ
Artículo publicado en Annals of Surgery

Lipin-2 regulates NLRP3 inflammasome by affecting P2X7 receptor activation

MIREN ITZIAR SANJUAN GARCIA
Gema Lordén,1,3 Itziar Sanjuán-García,1,3 Nagore de Pablo,1,3 Clara Meana,1,3 Inés Alvarez-Miguel,1,2 M. Teresa Pérez-García,1,2 Pablo Pelegrín,4 Jesús Balsinde,1,3 and María A. Balboa1,3

PUBLICACIÓN PAPER TESIS

PALOMA GARCÍA CASAS
"Inhibition of Sarco-Endoplasmic Reticulum Ca2+ ATPase Extends the lifespan in C. Elegans worms" García-Casas P, Arias-del-Vañ J, Alvarez Illera I, Fonteriz R, Montero M y Alvarez J.

Myelin extracellular leaflet compaction requires apolipoprotein D membrane management to optimize lysosomal-dependent recycling and glycocalyx removal.

RAQUEL PASCUA MAESTRO
Myelin extracellular leaflet compaction requires apolipoprotein D membrane management to optimize lysosomal-dependent recycling and glycocalyx removal. García-Mateo N, Pascua-Maestro R, Pérez-Castellanos A, Lillo C, Sanchez D, Ganfornina MD. Glia. 2018 Mar;66(3):670-687. doi: 10.1002/glia.23274. Epub 2017 Dec 9.

Entrevista en la Matacara

RAQUEL PASCUA MAESTRO
Se trata de una revista de divulgación

The MTT-formazan assay: Complementary technical approaches and in vivo validation in Drosophila larvae. (Corresponding author).

RAQUEL PASCUA MAESTRO
The MTT-formazan assay: Complementary technical approaches and in vivo validation in Drosophila larvae. Drosophila larvae. Pascua-Maestro R, Corraliza-Gomez M, Diez-Hermano S, Perez-Segurado C, Ganfornina MD, Sanchez D. Acta Histochem. 2018 Apr;120(3):179-186. doi: 10.1016/j.acthis.2018.01.006. Epub 2018 Feb 1.

Biomedical Applications of Recombinant Proteins and Derived Polypeptides

Sergio Acosta Rodríguez
“Biomedical Applications of Recombinant Proteins and Derived Polypeptides” F. J. Arias, S. Acosta-Rodríguez, T. Flora, S. Serrano-Dúcar 2017 Chapter 8 of the book entitled “Biopolymers for Medical Applications”, edited by J. M. Ruso and P. Messina, CRC Press/Taylor & Francis Group. https://www.taylorfrancis.com/books/e/9781498744973/chapters/10.1201%2F9781315368863-13

Elastin like recombinamers, a modular design to form nanoparticles and hydrogels for medical applications

Sergio Acosta Rodríguez
“Elastin like recombinamers, a modular design to form nanoparticles and hydrogels for medical applications” J. C. Rodríguez Cabello, S. Acosta-Rodríguez, M. González, I. González de Torre, M. Alonso In press Chapter of the book entitled “Self-Assembling Biomaterials: Molecular Design, Characterization and Application in Biology and Medicine”, Elsevier.

Elastin-like Proteins - Modular Design for Self-Assembling

Sergio Acosta Rodríguez
“Elastin like Proteins – Molecular Design for Self-Assembling” J. C. Rodríguez Cabello, I. González de Torre, S. Acosta, S. Salinas, M. Herrero Chapter 4 of the book Self-assembling Biomaterials. 2018, Pages 49–78 https://www.sciencedirect.com/science/article/pii/B9780081020159000046

Förster Resonance Energy Transfer-Paired Hydrogel Forming Silk-Elastin-Like Recombinamers by Recombinant Conjugation of Fluorescent Proteins

ARTURO IBAÑEZ FONSECA
Revista: Bioconjugate Chemistry. DOI: 10.1021/acs.bioconjchem.6b00738

Bone regeneration mediated by a bioactive and biodegradable ECM-like hydrogel based on elastin-like recombinamers

ARTURO IBAÑEZ FONSECA
Revista: Tissue Engineering Part A. DOI: 10.1089/ten.TEA.2017.0047

Elastin-like Polymers: Properties, Synthesis and Applications

ARTURO IBAÑEZ FONSECA
Revista: Encyclopedia of Polymer Science and Technology. DOI: 10.1002/0471440264.pst656

Regeneration of hyaline cartilage promoted by xenogeneic mesenchymal stromal cells embedded within elastin-like recombinamer-based bioactive hydrogels

ARTURO IBAÑEZ FONSECA
Revista: Journal of Materials Science: Materials in Medicine. DOI: 10.1007/s10856-017-5928-1

Biocompatibility of two model elastin-like recombinamer-based hydrogels formed through physical or chemical crosslinking for various applications in t

ARTURO IBAÑEZ FONSECA
Revista: Journal of Tissue Engineering and Regenerative Medicine

A dangerous liaison: Leptin and sPLA2-IIA join forces to induce proliferation and migration of astrocytoma cells Rubén Martín, Claudia Cordova, Bea

BEATRIZ ROSA GUTIERREZ MIRANDA
https://doi.org/10.1371/journal.pone.0170675

Netrin¿1 and multiple sclerosis: a new biomarker for neuroinflammation' P Mulero, C Córdova, M Hernández, R Martín, B Gutiérrez, JC Muñoz, N Redondo,

BEATRIZ ROSA GUTIERREZ MIRANDA
DOI: 10.1111/ene.13340

"The impact of obesity in the cardiac lipidomic and its consequences in the cardiac damage observed in obese rats." Marín-Royo G, Martínez-Martínez E,

BEATRIZ ROSA GUTIERREZ MIRANDA
Clin Investig Arterioscler. 2017 Aug 28. pii: S0214-9168(17)30090-6. doi: 10.1016/j.arteri.2017.07.004.

Relation between serum levels of chemotaxis-related factors and the presence of coronary artery calcification as expression of subclinical atheroscler

BEATRIZ ROSA GUTIERREZ MIRANDA
https://doi.org/10.1016/j.clinbiochem.2017.08.012

Superior accuracy of mid-regional proadrenomedullin for mortality prediction in sepsis with varying levels of illness severity.

CRISTINA ANDRES LEDESMA
La ProADM (proadrenomedulina) es un biomarcador que ha demostrado en los últimos años una gran utilidad como predictor de la mortalidad en Sepsis.

The impact of obesity in the cardiac lipidomic and its consequences in the cardiac damage observed in obese rats. 2017 Aug 28. pii: S0214-9168(17)3009

ISABEL GALLARDO ROMERO
Marín-Royo G, Martínez-Martínez E, Gutiérrez B, Jurado-López R, Gallardo I, Montero O, Bartolomé MV, Román JAS, Salaices M, Nieto ML, Cachofeiro V.

Functional roles of MICU1 and MICU2 in mitochondrial Ca(2+) uptake.

JESICA ARIAS DEL VAL
Matesanz-Isabel J, Arias-del-Val J, Alvarez-Illera P, Fonteriz RI, Montero M, Alvarez J. Biochim Biophys Acta. 2016 Jun;1858(6):1110-7.

Modulation of Calcium Entry by Mitochondria

JESICA ARIAS DEL VAL
Fonteriz R, Matesanz-Isabel J, Arias-Del-Val J, Alvarez-Illera P, Montero M, Alvarez J. Adv Exp Med Biol. 2016;898:405-21.

"Pharynx mitochondrial [Ca2+] dynamics in live C.elegans worms during aging"

JESICA ARIAS DEL VAL
Pilar Alvarez-Illera, Paloma García-Casas, Jessica Arias-del-Val, Rosalba I.Fonteriz, Javier Alvarez and Mayte Montero; Oncotarget June 22, 2017

Muscling in on TRP channels in vascular smooth muscle cells and cardiomyocytes.

LUCÍA ALONSO CARBAJO
Cell Calcium. 2017 Sep;66:48-61. doi: 10.1016/j.ceca.2017.06.004. Epub 2017 Jun 15.

María Teresa Alonso, Macarena Rodríguez-Prados, Paloma Pavas-Navarro, Jonathan Rojo-Ruiz, Javier García-Sancho. Using aequorin probes to measure Ca2+

MACARENA RODRIGUEZ VALLE
Using aequorin probes to measure Ca2+ in intracellular organelles

María Teresa Alonso, Jonathan Rojo-Ruiz, Paloma Navas-Navarro, Macarena Rodríguez-Prados, Javier García-Sancho. Measuring Ca2+ inside intracellular o

MACARENA RODRIGUEZ VALLE
Measuring Ca2+ inside intracellular organelles with luminescent and fluorescent aequorin-based sensors

Genetic dissection of the BRCA2 promoter and transcriptional impact of DNA variants

MARIA EUGENIA FRAILE BETHENCOURT
Articulo sometido, en vías de aceptación.

Functional classification of DNA variants by hybrid minigenes: Identification of 30 spliceogenic variants of BRCA2 exons 17 and 18.

MARIA EUGENIA FRAILE BETHENCOURT
PLoS Genet. 2017 Mar 24;13(3):e1006691. doi: 10.1371/journal.pgen.1006691. eCollection 2017.

Guinea Pig Oxygen-Sensing and Carotid Body Functional Properties Gonzalez-Obeso E, Docio I, Olea E, Cogolludo A, Obeso A, Rocher A, Gomez-Niño A

MARÍA INMACULADA DOCIO CUADRADO
Front Physiol. 2017 May 8;8:285. doi: 10.3389/fphys.2017.00285. eCollection 2017.

"In Vitro Aging Promotes Endoplasmic Reticulum (ER)-mitochondria Ca2+ Cross Talk and Loss of Store-Operated Ca2+ Entry (SOCE) in Rat Hippocampal Neuro

MONICA GARCIA DURILLO
Autores: Calvo-Rodríguez M, García-Durillo M, Villalobos C, Núñez L.

"Aging enables Ca2+ overload and apoptosis induced by amyloid ß oligomers in rat hippocampal neurons: neuroprotection by non-steroidal anti-inflammato

MONICA GARCIA DURILLO
Autores: Calvo-Rodríguez, M., M. García-Durillo, C. Villalobos and L. Núñez (2016).

"Aging and amyloid ß oligomers enhance TLR4 expression, LPS-induced Ca2+ responses, and neuron cell death in cultured rat hippocampal neurons"

MONICA GARCIA DURILLO
Autores: Calvo-Rodríguez, M., C. de la Fuente, M. García-Durillo, C. García-Rodríguez, C. Villalobos and L. Núñez

Leptolide Improves Insulin Resistance in Diet-Induced Obese Mice.

PABLO VILLA PEREZ
Mar Drugs. 2017 Sep 15;15(9). pii: E289. doi: 10.3390/md15090289.

Protecting cells by protecting their vulnerable lysosomes: Identification of a new mechanism for preserving lysosomal functional integrity upon oxidat

RAQUEL PASCUA MAESTRO
Pascua-Maestro R, Diez-Hermano S, Lillo C, Ganfornina MD, Sanchez D. PLoS Genet. 2017 Feb 9;13(2):e1006603. Doi: 10.1371/journal.pgen.1006603

Modulation of brain network parameters associated with subclinical psychotic symptoms

ALBA LUBEIRO JUÁREZ
Artículos: Progress in Neuro-Psychopharmacology & Biological Psychiatry

Elevated midline parietal gamma band noise power in schizophrenia but not in bipolar patients

ALBA LUBEIRO JUÁREZ
Revista: European archives of Psychiatry and Clinical Neurosciences

Identification of two clusters within schizophrenia with different structural, functional and clinical character

ALBA LUBEIRO JUÁREZ
Revista: Progress in Neuro-Psychopharmacology & Biological Psychiatry

Encyclopedia of Biomedical Polymers and Polymeric Biomaterials (EBPP).Taylor and Francis, 2014

ALICIA FERNANDEZ COLINO
Elastin-like Recombinamers

Biomacromolecules. 15 - 10, pp. 3781 - 3793. 2014

ALICIA FERNANDEZ COLINO
Self-Organized ECM-Mimetic Model Based on an Amphiphilic Multiblock Silk-Elastin-Like Corecombinamer

Biomacromolecules. 16 - 10, pp. 3389 - 3398. 2015

ALICIA FERNANDEZ COLINO
Amphiphilic Elastin-Like Block Co-Recombinamers Containing Leucine Zippers

Biotechnology Journal. 6, pp. 1 - 13. 2011

ALICIA FERNANDEZ COLINO
Elastin-like Recombinamers: Biosynthetic Strategies and Biotechnological Applications

Advances in Biochemical Engineering/Biotechnology. Biofunctionalisation, pp. 1 - 35. Springer, 2010

ALICIA FERNANDEZ COLINO
Recombinamers: Combining Molecular Complexity with Diverse Bioactivities for Advanced Biomedical and Biotechnological Applications

Current Topics in Medicinal Chemistry. 14, pp. 819 - 836. 2014

ALICIA FERNANDEZ COLINO
Recent contributions of elastin-like recombinamers to biomedicine and nanotechnology

Biomecánica. pp. 37 - 45. 2011

ALICIA FERNANDEZ COLINO
Los polímeros tipo elastina y su utilización como tags para la purificación de proteínas.

Biomaterials Surface Science. pp. 239 - 268. Wiley-VCH Verlag GmbH & Co. KGaA, 2013

ALICIA FERNANDEZ COLINO
Bioactive and Smart Hydrogel Surfaces

Bioconjugate Chemistry. 26 - 7, pp. 1252 - 1265. 2015.

ALICIA FERNANDEZ COLINO
Nanotechnological Approaches to Therapeutic Delivery Using Elastin-Like Recombinamers

Phospholipid sources for adrenic acid mobilization in RAW 264.7 macrophages. Comparison with arachidonic acid

CARLOS GUIJAS MATE
Biochimica et Biophysica Acta, 1821:1386-1393.

Group V secreted phospholipase A2 is up-regulated by interleukin-4 in human macrophages and mediates phagocytosis via hydrolysis of ethanolamine phosp

CARLOS GUIJAS MATE
Journal of Immunology, 194: 3327-3339.

Opposite cross-talk by oleate and palmitate on insulin signaling in hepatocytes through macrophage activation

CARLOS GUIJAS MATE
Journal of Biological Chemistry, 290:11663-77.

Cytosolic group IVA and calcium-independent group VIA phospholipases A2 act on distinct phospholipid pools in zymosan-stimulated mouse peritoneal macr

CARLOS GUIJAS MATE
Journal of Immunology, 192: 752-762.

Lipin-1 integrates lipid synthesis with proinflammatory responses during TLR activation in macrophages

CARLOS GUIJAS MATE
Journal of Immunology, 193: 4614-4622.

Influence of Cellular Arachidonic Acid Levels on Phospholipid Remodeling and CoA-independent Transacylase Activity in Human Monocytes and U937 Cells

CARLOS GUIJAS MATE
Biochimica et Biophysica Acta, 1811: 97-103

Subcellular localization and role of lipin-1 in human macrophages

CARLOS GUIJAS MATE
Journal of Immunology, 186: 6004-6013

Simultaneous Activation of p38 and JNK by Arachidonic Acid Stimulates the Cytosolic Phospholipase A2-dependent Synthesis of Lipid Droplets in Human Mo

CARLOS GUIJAS MATE
Journal of Lipid Research, 53: 2343¿2354

A phosphatidylinositol species acutely generated by activated macrophages regulates innate immune responses

CARLOS GUIJAS MATE
Journal of Immunology, 190: 5169-5177

Phospholipase A2 regulation of lipid droplet formation

CARLOS GUIJAS MATE
Biochim. Biophys. Acta, 1841: 1661-1671.

Red Ear and More: Facial and Extrafacial Erythema Accompanying Migraine Attacks.

ELENA MARTINEZ VELASCO
Publicación en revista internacional.

Headache with transient neurological deficit: a case report with hemispheric hypoperfusion and without lymphocytosis.

ELENA MARTINEZ VELASCO
Publicación en revista internacional.

Confusional state in HaNDL syndrome: an uncommon clinical manifestation.

ELENA MARTINEZ VELASCO
Publicación en revista internacional.

Embryonic cerebrospinal fluid in brain development: neural progenitor control

Jose Francisco Lamus Molina
Croat Med J. 2014 Aug 28;55(4):299-305. (Q2 IF: 1.305)

Retinoic Acid, under Cerebrospinal Fluid Control, Induces Neurogenesis during Early Brain Development

Jose Francisco Lamus Molina
J Dev Biol. 2014;2(2):72-83. (Indexada: Emerging Sources Citation Index (ESCI ¿ Web of Science) ISSN 2221-3759

Embryonic cerebrospinal fluid activates neurogenesis of neural precursors within the subventricular zone of the adult mouse brain

Jose Francisco Lamus Molina
Cells Tissues Organs. 2013;198(5):398-404. (Q1 IF: 2.137)

Navas-Navarro P, Rojo-Ruiz J, Rodriguez-Prados M, Ganfornina MD1, Looger LL, Alonso MT, García-Sancho J.

MACARENA RODRIGUEZ VALLE
GFP-Aequorin Protein Sensor for Ex Vivo and In Vivo Imaging of Ca(2+) Dynamics in High-Ca(2+) Organelles.Cell Chem Biol. 2016 Jun 23;23(6):738-45

López-Doménech et al., 2012

MACARENA RODRIGUEZ VALLE
The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2. Nat Commun. 8;3:814

Jose C. Rodríguez Cabello et al. Nanotechnological Approaches to Therapeutic Delivery Using Elastin-Like Recombinamers. Bioconjugate chemistry.26 - 7

MARIA JESUS PIÑA LANCHO
Segundo autor Maria J. Piña

Rodríguez-Cabello, J.C., et al., Bioactive and Smart Hydrogel Surfaces, in Biomaterials Surface Science. 2013, Wiley-VCH Verlag GmbH & Co. KGaA. p. 23

MARIA JESUS PIÑA LANCHO
Capítulo libro

Maria J. Piña et al. Elastin-like recombinamers with acquired functionalities for gene-delivery applications. Journal of Biomedical ResearchA. 10-103

MARIA JESUS PIÑA LANCHO
Primer autor. Maria J. Piña

Piña, M.J., et al., Biocompatible ELR-Based Polyplexes Coated with MUC1 Specific Aptamers and Targeted for Breast Cancer Gene Therapy. Molecular Pharm

MARIA JESUS PIÑA LANCHO
Maria J. Piña como primer autor

The dynamics of mitochondrial Ca2+ fluxes. (2010) Biochim Biophys Acta. 1797, 1727-1735. ISSN 0006-3002.

PABLO MANUEL MONTENEGRO ESCUDERO
De la Fuente, S., Montenegro, P., Fonteriz, R.I., Moreno, A., Lobatón, C.D., Montero, M., and Álvarez, J. (2010) Biochim Biophys Acta. 1797, 1727-1735

In vivo Ca2+ imaging in the endoplasmic reticulum with an optimized GFP-aequorin sensor. Paloma Navas-Navarro, Jonathan Rojo-Ruiz, Macarena Rodriguez-

PALOMA NAVAS NAVARRO
En revisión.

Capitulo de un libro

Tatjana Flora
Book Chapter CRCPress/Taylor&Francis Biopolymer for medical Applications

EN REVISIÓN:¿Aging without Apolipoprotein D: Molecular and cellular modifications in the hippocampus and cortex¿

RAQUEL PASCUA MAESTRO
Diego Sánchez. Raquel Bajo-Grañeras, Manuela del Caño-Espinel, Rosa García-Centeno, Nadia García-Mateo, Raquel Pascua-Maestro, Maria Ganfornina.